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        格式:Anilab Software & Instruments Co., Ltd., China

        Operant Behavior & I.V. Drug Self-Administration

        • Huang X, Chen YY, Shen Y, Cao X, Li A, Liu Q, Li Z, Zhang LB, Dai W, Tan T, Arias-Carrion O, Xue YX, Su H, Yuan TF. Methamphetamine abuse impairs motor cortical plasticity and function. Mol Psychiatry. 2017 Sep;22(9):1274-1281. doi: 10.1038/mp.2017.143. Epub 2017 Jul 25.
        • Zhang JJ, Kong Q. Locomotor activity: A distinctive index in morphine self-administration in rats. PLoS One. 2017 Apr 5;12(4):e0174272. doi: 10.1371/journal.pone.0174272. eCollection 2017.
        • Cui Y, Lv G, Jin S, Peng J, Yuan J, He X, Gong H, Xu F, Xu T, Li H. A Central Amygdala-Substantia Innominata Neural Circuitry Encodes Aversive Reinforcement Signals. Cell Rep. 2017 Nov 14;21(7):1770-1782. doi: 10.1016/j.celrep.2017.10.062.
        • Li Y, He Y, Chen M, Pu Z, Chen L, Li P, Li B, Li H, Huang ZL, Li Z, Chen JF. Optogenetic Activation of Adenosine A2A Receptor Signaling in the Dorsomedial Striatopallidal Neurons Suppresses Goal-Directed Behavior. Neuropsychopharmacology. 2016 Mar;41(4):1003-13. doi: 10.1038/npp.2015.227. Epub 2015 Jul 28.
        • Zhao Y, Zhang J, Yang H, Cui D, Song J, Ma Q, Luan W, Lai B, Ma L, Chen M, Zheng P.Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 receptors in mPFC neurons projecting to the basolateral amygdala. BMC Biol. 2017 Dec 27;15(1):128. doi: 10.1186/s12915-017-0467-2.
        • Cao DN, Song R, Zhang SZ, Wu N, Li J. Nucleus accumbens hyperpolarization-activated cyclic nucleotide-gated channels modulate methamphetamine self-administration in rats.Psychopharmacology (Berl). 2016 Aug;233(15-16):3017-29. doi: 10.1007/s00213-016-4349-z. Epub 2016 Jun 22.
        • Li QQ, Sun CY, Luo YX, Xue YX, Meng SQ, Xu LZ, Chen N, Deng JH, Zhai HF, Kosten TR, Shi J, Lu L, Sun HQ. A conjugate vaccine attenuates morphine- and heroin-induced behavior in rats. Int J Neuropsychopharmacol. 2014 Dec 7;18(5). pii: pyu093. doi: 10.1093/ijnp/pyu093.
        • Xuekun Ding, Yanhua Qiao, Chengji Piao, Xigeng Zheng, Zhengkui Liu and Jing Liang.N-methyl-D-aspartate receptor-mediated glutamate transmission in nucleus accumbens plays a more important role than that in dorsal striatum in cognitive flexibility. Front. Behav. Neurosci., 05 September 2014 | doi: 10.3389/fnbeh.2014.00304 [IF: 4.2]
        • Mu Li, Wen-jie Liu, Bin Lu, Yu-hua Wang and Jing-gen Liu. Differential expression of Arc in the mesocorticolimbic system is involved in drug and natural rewarding behavior in rats. Acta Pharmacologica Sinica 2013;34:1013-1024 [IF: 2.496]
        • Zhuo Liu, Jian-Jun Zhang, Xiao-Dong Liu, Long-Chuan Yu. Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neuroscience Letters 2012; 518(2):167–171 [IF: 2.055]
        • Kai Yue, Baomiao Ma, Qin Ru, Lin Chen, Yongping Gan, Daisong Wang, Guozhang Jin, c, Chaoying Li.The dopamine receptor antagonist levo-tetrahydropalmatine attenuates heroin self-administration and heroin-induced reinstatement in rats.Pharmacology Biochemistry and Behavior 2012;102(1):1-5;[IF: 2.82]
        • Chun Zhao et al. Chronic treatment with curcumin enhances methamphetamine locomotor sensitization and cue-induced reinstatement of methamphetamine self-administration. Pharmacology Biochemistry and Behavior 2012;102(4):55-561[IF: 2.82]
        • L Guo, et al. DBS of nucleus accumbens on heroin seeking behaviors in self-administering rats. Drug and Alcohol Dependence. Available online 11 October 2012[IF: 3.278]
        • Yan-Xue Xue, Yi-Xiao Luo, Ping Wu, Hai-Shui Shi, Li-Fen Xue, Chen Chen, Wei-Li Zhu, Zeng-Bo Ding, Yan-ping Bao, Jie Shi, David H. Epstein, Yavin Shaham, and Lin Lu. A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and Relapse. Science 13 April 2012: 241-245.[IF: 31.477]
        • Xiuyi Lu, Chun Zhao, Li Zhang, Baomiao Ma, Zhongze Lou, Yan Sun, Junfeng Chen, Wei Wu, Thomas J.R. Beveridge, Wenhua Zhou, Yu Liu.The effects of rearing condition on methamphetamine self-administration and cue-induced drug seeking. Drug and Alcohol Dependence. 2012; 124(3):288–298[IF: 3.278]
        • Guan-Yi Lu, Ning Wu, Zhao-Long Zhang, Jing Ai, Jin Li.Effects of d-cycloserine on extinction and reinstatement of morphine-induced conditioned place preference. Neuroscience Letters 2011; 503(3): 196–199[IF: 2.055]
        • Bin Lu, Mu Li, Yuan-yuan Hou, Jie Chen, Zhi-qiang Chi and Jing-gen Liu. Initial experience of heroin use under a two-chained operant schedule influences drug-seeking behavior after one month of abstinence. Acta Pharmacologica Sinica. 2010; 31: 387–392[IF: 2.496]
        • Xi Wang, Yi-xiao Luo, Ying-ying He, Fang-qiong Li, Hai-shui Shi, Li-fen Xue, Yan-xue Xue, and Lin Lu. Nucleus Accumbens Core Mammalian Target of Rapamycin Signaling Pathway Is Critical for Cue-Induced Reinstatement of Cocaine Seeking in Rats. The Journal of Neuroscience 2010; 30(38): 12632-12641[IF: 6.747]
        • Li M1, Liu WJ, Lu B, Wang YH, Liu JG. Differential expression of Arc in the mesocorticolimbic system is involved in drug and natural rewarding behavior in rats. Acta Pharmacol Sin. 2013 Aug;34(8):1013-24. doi: 10.1038/aps.2013.28. Epub 2013 May 27. 【runway DSA】
        • Liu Z, Liu XD, Zhang JJ, Yu LC. Increases in αCaMKII phosphorylated on Thr286 in the nucleus accumbens shell but not the core during priming-induced reinstatement of morphine-seeking in rats. Neurosci Lett. 2012 Sep 20;526(1):39-44. doi: 10.1016/j.neulet.2012.07.042. Epub 2012 Aug 2.
        • Niu Y, Dai Z, Liu W, Zhang C, Yang Y, Guo Z, Li X, Xu C, Huang X, Wang Y, Shi YS, Liu JJ. Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. Elife. 2017 Jan 30;6. pii: e20991. doi: 10.7554/eLife.20991.
        • Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11(9):1608-22. doi: 10.1080/15548627.2015.1072669.
        • Chen FF, Huo FQ, Xiong H, Wan Q, Zheng YN, Du WJ, Mei ZN. Analgesic effect of total flavonoids from Sanguis draxonis on spared nerve injury rat model of neuropathic pain. Phytomedicine. 2015 Nov 15;22(12):1125-32. doi: 10.1016/j.phymed.2015.08.011. Epub 2015 Sep 16.
        • Hai-Feng Lu,Peng-Fei Wu, Yuan-Jian Yang, Wen Xiao, Jun Fan, Jing Liu, Yuan-Long Li, Yi Luo, Zhuang-Li Hu, You Jin, Fang Wang, and Jian-Guo Chen. Interactions between N-Ethylmaleimide-Sensitive Factor and GluR2 in the Nucleus Accumbens Contribute to the Expression of Locomotor Sensitization to Cocaine.The Journal of Neuroscience, 2014, 34(10):3493-3508[IF: 6.747]
        • Kui Li, Ji-Wei Liu, Zhi-Chuan Zhu, Hong-Tao Wang, Yong Zu, Yong-Jie Liu, Yan-Hong Yang, Zhi-Qi Xiong,Xu Shen, Rui Chen, Jing Zheng, Ze-Lan Hu.DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test. Int J Clin Exp Pathol 2014;7(10):6486-6492
        • Ying Zhang,Ning Wang,Ping Su,Jie Lu,Yun Wang.Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice. Neuroscience Bulletin. 10/2014; DOI: 10.1007/s12264-014-1473-9[IF: 1.832]
        • Ning Wang, Ping Su, Ying Zhang, Jie Lu, Baoming Xing, Kai Kang, Wenqi Li and Yun Wang. Protein Kinase D1-Dependent Phosphorylation of Dopamine D1 Receptor Regulates Cocaine-Induced Behavioral Responses. Neuropsychopharmacology (23 December 2013) | doi:10.1038/npp.2013.341[IF: 5.264]
        • Rongrong Hu, Rui Song, Rifang Yang, Ruibin Su, Jin Li. The dopamine D3 receptor antagonist YQA14 that inhibits the expression and drug-primed reactivation of morphine-induced conditioned place preference in rats.European Journal of Pharmacology; 2013;720(1-3):212-217[IF: 2.684]
        • Jie-Shu You,Min Peng,Jin-Li Shi,Hu-Zhan Zheng,Yong Liu,Bao-Sheng Zhao,and Jian-You Guo. Evaluation of anxiolytic activity of compound Valeriana jatamansi Jones in mice. BMC Complement Altern Med. 2012; 12: 223.[IF: 1.877]
        Startle Reflex
        • Xinwen Dong and Yonghui Li. Peritraumatic startle response predicts the vulnerability to develop PTSD-like behaviors in rats: a model for peritraumatic dissociation. Front. Behav. Neurosci., 28 January 2014 | doi: 10.3389/fnbeh.2014.00014.[IF: 4.2]
        Conditioned Fear
        • Zhu Y, Du R, Zhu Y, Shen Y, Zhang K, Chen Y, Song F, Wu S, Zhang H, Tian M. PET Mapping of Neurofunctional Changes in a Posttraumatic Stress Disorder Model. J Nucl Med. 2016 Sep;57(9):1474-7. doi: 10.2967/jnumed.116.173443. Epub 2016 Mar 16.
        Conditioned Place Preference
        • Wang N, Su P, Zhang Y, Lu J, Xing B, Kang K, Li W, Wang Y. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology. 2014 Apr;39(5):1290-301. doi: 10.1038/npp.2013.341. Epub 2013 Dec 23.
        • J Wang, Y Wang, Y Hou, T Xi, Y Liu, J Liu. The small GTPase RhoA, but not Rac1, is essential for conditioned aversive memory formation through regulation of actin rearrangements in rat dorsal hippocampus. Acta Pharmacologica Sinica, 2013; 34: 811–818.[IF: 2.496]
        • Yuan-yuan Hou, Yao Liu, Shuo Kang, Chuan Yu, Zhi-qiang Chi and Jing-gen Liu.Glutamate receptors in the dorsal hippocampus mediate the acquisition, but not the expression, of conditioned place aversion induced by acute morphine withdrawal in rats. Acta Pharmacologica Sinica 2009;30: 1385–1391[IF: 2.496]
        Conflict Drinking Test
        • Guanyin Chen,Lining Feng, Zhi Liu, Yongzhu Sun, Haifeng Chang, Pengcheng Cui.Both Central and Peripheral Auditory Systems Are Involved in Salicylate-Induced Tinnitus in Rats: A Behavioral Study. PlOS one Published: September 30, 2014 DOI: 10.1371/journal.pone.0108659[IF: 3.534]
        • Cheng L, Pan GF, Sun XB, Huang YX, Peng YS, Zhou LY. Evaluation of anxiolytic-like effect of aqueous extract of asparagus stem in mice. Evid Based Complement Alternat Med. 2013;2013:587260. doi: 10.1155/2013/587260. Epub 2013 Nov 20.
        Maze Tracking
        • Wang X, Chen Y, Wang Q, Sun L, Li G, Zhang C, Huang J, Chen L, Zhai H. Support for Natural Small-Molecule Phenols as Anxiolytics. Molecules. 2017 Dec 6;22(12). pii: E2138. doi: 10.3390/molecules22122138.
        • Dong D, Mao Y, Huang C, Jiao Q, Pan H, Ma L, Wang R. Astrocytes mediated the nootropic and neurotrophic effects of Sarsasapogenin-AA13 via upregulating brain-derived neurotrophic factor. Am J Transl Res. 2017 Sep 15;9(9):4015-4025. eCollection 2017.
        • Li D, Zhang L, Huang X, Liu L, He Y, Xu L, Zhang Y, Zhao T, Wu L, Zhao Y, Wu K, Wu Y, Fan M, Zhu L.WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation. Neurosci Bull. 2017 Jun;33(3):292-298. doi: 10.1007/s12264-016-0095-9. Epub 2017 Jan 17.
        • Zhang H, Kang E, Wang Y, Yang C, Yu H, Wang Q, Chen Z, Zhang C, Christian KM, Song H, Ming GL, Xu Z. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016 Jun 1;7. doi: 10.1038/ncomms11773. Erratum in: Nat Commun. 2018 Jul 18;9:16229.
        • Li J, Liu QT, Chen Y, Liu J, Shi JL, Liu Y, Guo JY. Involvement of 5-HT1A Receptors in the Anxiolytic-Like Effects of Quercitrin and Evidence of the Involvement of the Monoaminergic System. Evid Based Complement Alternat Med. 2016;2016:6530364. doi: 10.1155/2016/6530364. Epub 2016 May 19.
        • Kui Li, Ji-Wei Liu, Zhi-Chuan Zhu, Hong-Tao Wang, Yong Zu, Yong-Jie Liu, Yan-Hong Yang, Zhi-Qi Xiong,Xu Shen, Rui Chen, Jing Zheng, Ze-Lan Hu.DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test. Int J Clin Exp Pathol 2014;7(10):6486-6492[IF: 1.783]
        Optogenetic Control
        • Yang X, Yao C, Tian T, Li X, Yan H, Wu J, Li H, Pei L, Liu D, Tian Q, Zhu LQ, Lu Y. A novel mechanism of memory loss in Alzheimer's disease mice via the degeneration of entorhinal-CA1 synapses. Mol Psychiatry. 2018 Feb;23(2):199-210. doi: 10.1038/mp.2016.151. Epub 2016 Sep 27.
        • Yan Li, Zhibing Tan, Zhigang Li, Zhongsheng Sun, Shunmin Duan and Wei Li. Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice. Bioscience Reports (2012) doi:10.1042/BSR20110107
        • Qian-Qian Li, Yi-Xiao Luo, Cheng-Yu Sun, Yan-Xue Xue, Wei-Li Zhu, Hai-Shui Shi, Hai-Feng Zhai, Jie Shi, Lin Lu.A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats. J. Neurochem. (2011) 10.1111/j.1471-4159.2011.07502.x
        • Xiao-Rui Cheng, Yong Yang, Wen-Xia Zhou, and Yong-Xiang Zhang. Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. Neurobiology of Learning and Memory. 2011;95(3):361-375
        • Ling-Di Yan,Yan-Li Liu, Lei Zhang, Hua-Jin Dong, Pei-Lan Zhou, Rui-Bin Su, Ze-Hui Gong, , and Pei-Tang Huan.Spinal antinociception of synthetic omega-conotoxin SO-3, a selective N-type neuronal voltage-sensitive calcium channel blocker, and its effects on morphine analgesia in chemical stimulus tests in rodent. European Journal of Pharmacology 2010;636(1-3):73-81
        • Ge Meng, Ning Wu, Cheng Zhang, Rui-Bin Su, Xin-Qiang Lu, Yin Liu, Liu-Hong Yun, Jian-Quan Zheng and Jin Li. Analgesic activity of ZC88, a novel N-type voltage-dependent calcium channel blocker, and its modulation of morphine analgesia, tolerance and dependence. European Journal of Pharmacology 2008;586(1-3):130-138
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